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Article

Aotearoa New Zealand Māori and Pacific Population-amplified Gout Risk Variants: CLNK Is a Separate Risk Gene at the SLC2A9 Locus.

The Journal of rheumatology - 1 Nov 2021

Ji Aichang, Shaukat Amara, Takei Riku, Bixley Matthew, Cadzow Murray, Topless Ruth K, Major Tanya J, Phipps-Green Amanda, Merriman Marilyn E, Hindmarsh Jennie Harré, Stamp Lisa K, Dalbeth Nicola, Li Changgui, Merriman Tony R

Abstract excerpt

OBJECTIVE: The Māori and Pacific (Polynesian) population of Aotearoa New Zealand has a high prevalence of gout. Our aim was to identify potentially functional missense genetic variants in candidate inflammatory genes amplified in frequency that may underlie the increased prevalence of gout in Polynesian populations. METHODS: A list of 712 inflammatory disease-related genes was generated. An in silico targeted...

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PMID: 34210831
DOI: 10.3899/jrheum.201684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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