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Article

The SLC2A9 nonsynonymous Arg265His variant and gout: evidence for a population-specific effect on severity.

Arthritis research & therapy - 9 Jun 2011

Hollis-Moffatt Jade E, Gow Peter J, Harrison Andrew A, Highton John, Jones Peter B B, Stamp Lisa K, Dalbeth Nicola, Merriman Tony R

Abstract excerpt

INTRODUCTION: The C allele of the nonsynonymous Arg265His (rs3733591) variant of SLC2A9 confers risk for gout in Han Chinese, Solomon Island and Japanese samples, with a stronger role in tophaceous gout. There is no evidence for an association with gout in Caucasian populations. In the present study, we tested rs3733591 for association with gout in New Zealand (NZ) Māori, Pacific Island and Caucasian samples....

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Identifiers

PMID: 21658257
DOI: 10.1186/ar3356
PMCID: PMC3218899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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