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Identification of a novel susceptibility locus at 16q23.1 associated with childhood acute lymphoblastic leukemia in Han Chinese.

Human molecular genetics - 1 Jul 2016

Shi Yongyong, Du Mulong, Fang Yongjun, Tong Na, Zhai Xiaowen, Sheng Xiaojing, Li Zhiqiang, Xue Yao, Li Jie, Chu Haiyan, Chen Jianhua, Song Zhijian, Shen Jiawei, Ji Jue, Li Xingwang, Hu Zhibin, Shen Hongbing, Xu Jianfeng, Wang Meilin, Zhang Zhengdong

Abstract excerpt

Recently, genome-wide association studies (GWAS) have identified several susceptibility loci for childhood acute lymphoblastic leukemia (ALL) in populations of European descent; only a few loci could be confirmed in Asian populations because of those populations' genetic heterogeneity. To identify genetic factors associated with childhood ALL risk in the Chinese population, we performed a three-stage GWAS of 1184...

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PMID: 27094129
DOI: 10.1093/hmg/ddw112

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