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Article

Association of TLX1 gene polymorphisms with the risk of acute lymphoblastic leukemia and B lineage acute lymphoblastic leukemia in Han Chinese children.

Journal of clinical laboratory analysis - 1 Sept 2020

Mei Endian, Wei Xubin, Gao Jiadong, Tian Xiaolong, Li Wei, Liu Li, Qian Cheng

Abstract excerpt

BACKGROUND: Studies on gene polymorphism association are centered on childhood acute lymphoblastic leukemia (ALL), a common hematological malignancy in children younger than 16 years. Single-nucleotide polymorphisms (SNPs) in some genes, such as ARID5B and CDKN2B, are associated with the risk of childhood ALL. T-cell leukemia homeobox 1 (TLX1), a member of the HOX gene family, was identified based on its abnormal...

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PMID: 32488880
DOI: 10.1002/jcla.23414
PMCID: PMC7521250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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