Article
Genetic susceptibility in childhood acute lymphoblastic leukemia.
Medical oncology (Northwood, London, England) - 13 Sept 2017
Gutierrez-Camino Angela, Martin-Guerrero Idoia, García-Orad Africa
Abstract excerpt
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and a leading cause of death due to disease in children. The genetic basis of ALL susceptibility has been supported by its association with certain congenital disorders and, more recently, by several genome-wide association studies (GWAS). These GWAS identified common variants in ARID5B, IKZF1, CEBPE, CDKN2A, PIP4K2A, LHPP and ELK3...
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