10p12.31-12.2 variants and risk of childhood acute lymphoblastic leukemia in a Chinese population.

Abstract excerpt

Acute lymphoblastic leukemia (ALL) is a clonal hematologic disease, and is the most common cause of childhood malignancy. Recently, a new locus was identified at 10p12.31-12.2 through a genome-wide association study (GWAS) that included racially and ethnically diverse populations. We conducted a replication study with 570 cases of ALL and 673 cancer-free controls to validated the association of this locus with...

Topics

Join the communities discussing this publication.

• Asian People
• Case-Control Studies
• Child, Preschool
• China
• Chromosomes, Human, Pair 10