Article
GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21.
Nature communications - 18 Jan 2018
Wiemels Joseph L, Walsh Kyle M, de Smith Adam J, Metayer Catherine, Gonseth Semira, Hansen Helen M, Francis Stephen S, Ojha Juhi, Smirnov Ivan, Barcellos Lisa, Xiao Xiaorong, Morimoto Libby, McKean-Cowdin Roberta, Wang Rong, Yu Herbert, Hoh Josephine, DeWan Andrew T, Ma Xiaomei
Abstract excerpt
Childhood acute lymphoblastic leukemia (ALL) (age 0-14 years) is 20% more common in Latino Americans than non-Latino whites. We conduct a genome-wide association study in a large sample of 3263 Californian children with ALL (including 1949 of Latino heritage) and 3506 controls matched on month and year of birth, sex, and ethnicity, and an additional 12,471 controls from the Kaiser Resource for Genetic...
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