Article
FOXO3 gene polymorphisms influence the risk of acute lymphoblastic leukemia in Chinese children.
Journal of cellular biochemistry - 1 Feb 2020
Yang Xu, Wu Xuedong, Fang Na, Liu Xiaoping, Liu Xiaodan, Yang Lihua, Huang Ke, Luo Ailing, Cai Mansi, Wu Fan, Jiang Hua, Xu Ling
Abstract excerpt
Acute lymphoblastic leukemia (ALL) is the most frequently diagnosed cancer in children and single-nucleotide polymorphisms (SNPs) in certain genes influence risk of ALL. Although FOXO3 had been demonstrated to be involved leukemia, the role of FOXO3 polymorphisms was still not clear. In the present study, we explored the association of FOXO3 SNPs with ALL risk in Chinese children. We genotyped four polymorphisms...
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