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Article

Genetic variants of CHRNA5-A3 and CHRNB3-A6 predict survival of patients with advanced non-small cell lung cancer.

Oncotarget - 3 May 2016

Wang Yang, Peng Xiaonu, Zhu Lijun, Hu Likuan, Song Yipeng

Abstract excerpt

Nicotinic acetylcholine receptors (nAChRs) play a key role in carcinogenesis and progression of lung cancer; and polymorphisms in CHRNA5-A3 and CHRNB3-A6, two gene clusters encoding nAChR subunits, have been associated with lung cancer risk. In this study, we investigated whether variants in the two gene clusters were associated with prognosis of advanced non-small cell lung cancer (NSCLC). A total of 165 stage...

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Source

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Identifiers

PMID: 27050379
DOI: 10.18632/oncotarget.8510
PMCID: PMC5041990

Genes

CHRNA5
CHRNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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