Article
Unmethylation of the CHRNB4 gene is an unfavorable prognostic factor in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Oct 2014
Yoo Seung Soo, Lee Su Man, Do Sook Kyung, Lee Won Kee, Kim Dong Sun, Park Jae Yong
Abstract excerpt
OBJECTIVES: Lung cancer is the leading cause of cancer-related deaths and is currently a major health problem owing to difficulties in diagnosis at the early stage of the disease. Changes in DNA methylation status have now been identified as a critical component in the initiation of lung cancer, and the detection of DNA methylation is expected to be an important method for the early diagnosis of lung cancer....
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