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Article

CHRNA3 polymorphism modifies lung adenocarcinoma risk in the Chinese Han population.

International journal of molecular sciences - 28 Mar 2014

He Ping, Yang Xue-Xi, He Xuan-Qiu, Chen Jun, Li Fen-Xia, Gu Xia, Jiang Ju-Hong, Liang Hui-Ying, Yao Guang-Yu, He Jian-Xing

Abstract excerpt

Recent genome-wide association studies (GWASs) have identified 15q25.1 as a lung cancer susceptibility locus. Here, we sought to explore the direct carcinogenic effects of genetic variants in this region on the risk of developing lung adenocarcinoma (ADC). Five common SNPs (rs8034191, rs16969968, rs1051730, rs938682, and rs8042374) spanning the 15q25.1 locus were assayed in a case-control study examining a cohort...

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Identifiers

PMID: 24686516
DOI: 10.3390/ijms15045446
PMCID: PMC4013574

Genes

CHRNA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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