A genetic variant in CHRNB3-CHRNA6 increases risk of esophageal squamous cell carcinoma in Chinese populations.

doi:10.1093/carcin/bgv019

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A genetic variant in CHRNB3-CHRNA6 increases risk of esophageal squamous cell carcinoma in Chinese populations.

Carcinogenesis - 1 May 2015

Song Yipeng, Wang Yang, Xu Li, Ma Jinbo, Chen Ercheng, Zang Rukun, Jia Weihua, Tao Xiaofeng, Hu Likuan

Abstract excerpt

Nicotinic acetylcholine receptors are important regulators of smoking behavior and tobacco carcinogenesis. We studied the association of the CHRNB3-A6 variant rs13280604 in relation to esophageal squamous cell carcinoma (ESCC) in Chinese populations. Two independent case-control studies were conducted. The first case-control study, consisted of 866 ESCC patients and 1621 healthy controls from Northern China, and...

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Identifiers

PMID: 25823894
DOI: 10.1093/carcin/bgv019

Genes

CHRNB3
CHRNA6

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