Article
Association of the CHRNA3 locus with lung cancer risk and prognosis in Chinese Han population.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2010
Niu Xiaomin, Chen Zhiwei, Shen Shengping, Liu Yun, Zhou Daizhan, Zhang Jie, Li Ziming, Yu Yongfeng, Liao Meilin, Lu Shun, He Lin
Abstract excerpt
INTRODUCTION: Recent genome-wide association studies in Caucasians revealed association with lung cancer risk of single nucleotide polymorphisms (SNPs) in the locus containing two nicotine acetylcholine receptor CHRNA genes. However, the reported risk SNPs are extremely rare in Asians. This study sought to identify other variants on CHRNA3 associated with lung cancer susceptibility and to explore whether SNPs of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
