Article
Correlation between polymorphisms of nicotine acetylcholine acceptor subunit CHRNA3 and lung cancer susceptibility.
Molecular medicine reports - 1 Dec 2012
Shen Bo, Shi Mei-Qi, Zheng Ma-Qing, Hu Sai-Nan, Chen Jia, Feng Ji-Feng
Abstract excerpt
Both environmental and genetic factors participate in the pathogenesis of lung cancer. The aim of this study was to explore the association between CHRNA3 polymorphisms of the nicotinic acetylcholine receptor gene and lung cancer risk in a hospital-based, case-controlled study. Single nucleotide polymorphisms (SNPs) in CHRNA3 rs3743073 (A>G) were determined using...
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