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Article

Association of CHRNA5-A3-B4 variation with esophageal squamous cell carcinoma risk and smoking behaviors in a Chinese population.

PloS one - 1 Jan 2013

Wang Yang, Wu Haijian, Liu Qiji, Wang Cuihong, Fu Lei, Wang Han, Zhu Wenjie, Fu Weijiang, Lv Yajuan, Wang Shikun, Hu Likuan

Abstract excerpt

BACKGROUND: CHRNA5-A3-B4, the gene cluster encoding nicotinic acetylcholine receptor subunits, is associated with lung cancer risk and smoking behaviors in people of European descent. Because cigarette smoking is also a major risk factor for esophageal squamous cell carcinoma (ESCC), we investigated the associations between variants in CHRNA5-A3-B4 and ESCC risk, as well as smoking behaviors, in a Chinese...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23844051
DOI: 10.1371/journal.pone.0067664
PMCID: PMC3699625

Genes

CHRNA5
CPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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