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Article

Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese.

PloS one - 1 Jan 2012

Yang Lei, Qiu Fuman, Lu Xiaoxiao, Huang Dongsheng, Ma Guanpei, Guo Yuan, Hu Min, Zhou Yumin, Pan Mingan, Tan Yigang, Zhong Haibo, Ji Weidong, Wei Qingyi, Ran Pixin, Zhong Nanshan, Zhou Yifeng, Lu Jiachun

Abstract excerpt

Recently, several genome-wide association studies (GWAS) have identified many susceptible single nucleotide polymorphisms (SNPs) for chronic obstructive pulmonary disease (COPD) and lung cancer which are two closely related diseases. Among those SNPs, some of them are shared by both the diseases, reflecting there is possible genetic similarity between the diseases. Here we tested the hypothesis that whether those...

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Identifiers

PMID: 23056235
DOI: 10.1371/journal.pone.0046071
PMCID: PMC3463594

Genes

CHRNA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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