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Article

CHRNA5 gene D398N polymorphism in Japanese lung adenocarcinoma.

The Journal of surgical research - 1 Jul 2010

Sasaki Hidefumi, Hikosaka Yu, Okuda Katsuhiro, Kawano Osamu, Yukiue Haruhiro, Yano Motoki, Fujii Yoshitaka

Abstract excerpt

BACKGROUND: Recently, to identify genetic factors that modify lung cancer risk, CHRNA5 non-synonymous variant amino acid position 398 (D398N) was identified. The site was a highly conserved in the second cellular loop of the nicotinic acetylcholine receptor subunit protein. MATERIALS AND METHODS: We have investigated CHRNA5 gene polymorphism status in 302 surgically treated lung adenocarcinoma cases from Nagoya...

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Share to Adenocarcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Nicotinic

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Source

Identifiers

PMID: 19577767
DOI: 10.1016/j.jss.2009.01.008

Genes

CHRNA5
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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