Article
Iris transillumination defect and its gene modulators do not correlate with intraocular pressure in the BXD family of mice.
Molecular vision - 1 Jan 2016
Lu Hong, Lu Lu, Williams Robert W, Jablonski Monica M
Abstract excerpt
PURPOSE: Intraocular pressure (IOP) is currently the only treatable phenotype associated with primary open angle glaucoma (POAG). Our group has developed the BXD murine panel for identifying genetic modulators of the various endophenotypes of glaucoma, including pigment dispersion, IOP, and retinal ganglion cell (RGC) death. The BXD family consists of the inbred progeny of crosses between the C57BL/6J (B6) strain...
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