Article
YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17.
Disease models & mechanisms - 1 Aug 2016
Nair K Saidas, Cosma Mihai, Raghupathy Narayanan, Sellarole Michael A, Tolman Nicholas G, de Vries Wilhelmine, Smith Richard S, John Simon W M
Abstract excerpt
A variety of inherited animal models with different genetic causes and distinct genetic backgrounds are needed to help dissect the complex genetic etiology of glaucoma. The scarcity of such animal models has hampered progress in glaucoma research. Here, we introduce a new inherited glaucoma model: the inbred mouse strain YBR/EiJ (YBR). YBR mice develop a form of pigmentary glaucoma. They exhibit a progressive...
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