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Article

Genetic dissection of the Gpnmb network in the eye.

Investigative ophthalmology & visual science - 13 Jun 2011

Lu Hong, Wang Xusheng, Pullen Matthew, Guan Huaijin, Chen Hui, Sahu Shwetapadma, Zhang Bing, Chen Hao, Williams Robert W, Geisert Eldon E, Lu Lu, Jablonski Monica M

Abstract excerpt

PURPOSE: To use a systematic genetics approach to investigate the regulation of Gpnmb, a gene that contributes to pigmentary dispersion syndrome (PDS) and pigmentary glaucoma (PG) in the DBA/2J (D2) mouse. METHODS: Global patterns of gene expression were studied in whole eyes of a large family of BXD mouse strains (n = 67) generated by crossing the PDS- and PG-prone parent (DBA/2J) with a resistant strain...

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Identifiers

PMID: 21398278
DOI: 10.1167/iovs.10-6493
PMCID: PMC3175941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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