Article

Genomic Locus Modulating Corneal Thickness in the Mouse Identifies <i>POU6F2</i> as a Potential Risk of Developing Glaucoma

2017-11-01

Abstract excerpt

<h4>Purpose: </h4> Central corneal thickness (CCT) is one of the most heritable ocular traits and it is also a phenotypic risk factor for primary open angle glaucoma (POAG). The present study uses the BXD Recombinant Inbred (RI) strains to identify novel quantitative trait loci (QTLs) modulating CCT in the mouse with the potential of identifying a molecular link between CCT and risk of developing POAG. Methods: Th...

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Literature Corpus work: 423450ca-fde0-511f-8f6e-961a47a8740d
DOI: 10.1101/212605

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