Article
Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice.
BMC genetics - 1 Jan 2001
Anderson M G, Smith R S, Savinova O V, Hawes N L, Chang B, Zabaleta A, Wilpan R, Heckenlively J R, Davisson M, John S W
Abstract excerpt
BACKGROUND: Glaucoma is a common disease but its molecular etiology is poorly understood. It involves retinal ganglion cell death and optic nerve damage that is often associated with elevated intraocular pressure. Identifying genes that modify glaucoma associated phenotypes is likely to provide insights to mechanisms of glaucoma. We previously reported glaucoma in DBA/2J mice caused by recessive alleles at two...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.