Article

BXD51: A Robust and Translational Mouse Model for Studying the Pathophysiology of Glaucoma

2026-07-25

Abstract excerpt

The aim of this study was to characterize the BXD51 mouse strain as a reproducible model of chronic progressive glaucoma. Unlike the highly susceptible DBA/2J (D2) mutant strain, BXD51 is a genetically stable recombinant inbred line derived from C57BL/6J (B6) and D2 parental lines. Longitudinal assessments of intraocular pressure (IOP), visual acuity (VA), contrast sensitivity (CS), and pattern electroretinogram (...

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Identifiers and source

Literature Corpus work: 04ff209c-dabe-590b-a739-bec3204b9e31
DOI: 10.64898/2026.07.21.739658

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