Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma.

Investigative ophthalmology & visual science - 1 Mar 2006

Inman Denise M, Sappington Rebecca M, Horner Philip J, Calkins David J

Abstract excerpt

PURPOSE: To investigate quantitatively the relationships between elevated intraocular pressure (IOP), axonal loss, and corneal thickness in the DBA/2 mouse model of glaucoma, to understand better how these factors contribute to disease progression. METHODS: IOP was measured with a handheld tonometer (Tono-Pen; Medtronic Solan, Jacksonville, FL) in 195 to 446 eyes of mice 2 to 10 months of age sampled from a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cornea
Share to Glaucoma, Angle-Closure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intraocular Pressure

Share to Mice, Inbred DBA

Share to Optic Disk

Share to Optic Nerve Diseases

Share to Retinal Ganglion Cells

Share to Tonometry, Ocular

Source

Identifiers

PMID: 16505033
DOI: 10.1167/iovs.05-0925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma.PMID 16505033Read ↗

Structural Changes of Retina in the Development of Glaucoma in DBA/2 MiceSemantic proximity Read ↗

Microarray Analysis of Retinal Gene Expression in the DBA/2J Model of GlaucomaSemantic proximity Read ↗

Dependency of intraocular pressure elevation and glaucomatous changes in DBA/2J and DBA/2J-Rj mice.Semantic proximity Read ↗

Regional Gene Expression in the Retina, Optic Nerve Head, and Optic Nerve of Mice with Experimental Glaucoma and Optic Nerve CrushSemantic proximity Read ↗

Advanced Age Worsens Phenotypes of Ocular Hypertension in Mice.Semantic proximity Read ↗

BXD51: A Robust and Translational Mouse Model for Studying the Pathophysiology of GlaucomaSemantic proximity Read ↗

Iris transillumination defect and its gene modulators do not correlate with intraocular pressure in the BXD family of mice.Semantic proximity Read ↗

Optic nerve damage in mice with a targeted type I collagen mutation.Semantic proximity Read ↗

Rod photoreceptor ribbon synapses in DBA/2J mice show progressive age-related structural changes.Semantic proximity Read ↗

Microglia respond to elevated intraocular pressure and synapse loss in the visual thalamus in a mouse model of glaucomaSemantic proximity Read ↗

Visual Function Correlates More Strongly with Glial Coverage than Axon Count Across Multiple Mouse StrainsSemantic proximity Read ↗

Impaired axonal transport at the optic nerve head contributes to neurodegeneration in a novel Cre-inducible mouse model of myocilin glaucomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.