Article
Expression quantitative trait analysis reveals fine germline transcript regulation in mouse lung tumors.
Cancer letters - 1 Jun 2016
Cotroneo Chiara E, Dassano Alice, Colombo Francesca, Pettinicchio Angela, Lecis Daniele, Dugo Matteo, De Cecco Loris, Dragani Tommaso A, Manenti Giacomo
Abstract excerpt
Gene expression modulates cellular functions in both physiologic and pathologic conditions. Herein, we carried out a genetic linkage study on the transcriptome of lung tumors induced by urethane in an (A/J x C57BL/6)F4 intercross population, whose individual lung tumor multiplicity (Nlung) is linked to the genotype at the Pulmonary adenoma susceptibility 1 (Pas1) locus. We found that expression levels of 1179 and...
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