Article
Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice.
Nature genetics - 1 Aug 2006
Liu Pengyuan, Wang Yian, Vikis Haris, Maciag Anna, Wang Daolong, Lu Yan, Liu Yan, You Ming
Abstract excerpt
We performed a whole-genome association analysis of lung tumor susceptibility using dense SNP maps ( approximately 1 SNP per 20 kb) in inbred mice. We reproduced the pulmonary adenoma susceptibility 1 (Pas1) locus identified in previous linkage studies and further narrowed this quantitative trait locus (QTL) to a region of less than 0.5 Mb in which at least two genes, Kras2 (Kirsten rat sarcoma oncogene 2) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
