Article
Multigenic nature of the mouse pulmonary adenoma progression 1 locus.
BMC genomics - 6 Mar 2013
Dassano Alice, Noci Sara, Galbiati Federica, Colombo Francesca, Trincucci Gaia, Pettinicchio Angela, Dragani Tommaso A, Manenti Giacomo
Abstract excerpt
BACKGROUND: In an intercross between the SWR/J and BALB/c mouse strains, the pulmonary adenoma progression 1 (Papg1) locus on chromosome 4 modulates lung tumor size, one of several measures of lung tumor progression. This locus has not been fully characterized and defined in its extent and genetic content. Fine mapping of this and other loci affecting lung tumor phenotype is possible using recombinant inbred...
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