Article
Analysis of allele-specific expression in mouse liver by RNA-Seq: a comparison with Cis-eQTL identified using genetic linkage.
Genetics - 1 Nov 2013
Lagarrigue Sandrine, Martin Lisa, Hormozdiari Farhad, Roux Pierre-François, Pan Calvin, van Nas Atila, Demeure Olivier, Cantor Rita, Ghazalpour Anatole, Eskin Eleazar, Lusis Aldons J
Abstract excerpt
We report an analysis of allele-specific expression (ASE) and parent-of-origin expression in adult mouse liver using next generation sequencing (RNA-Seq) of reciprocal crosses of heterozygous F1 mice from the parental strains C57BL/6J and DBA/2J. We found a 60% overlap between genes exhibiting ASE and putative cis-acting expression quantitative trait loci (cis-eQTL) identified in an intercross between the same...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
