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Article

Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus.

Cancer research - 1 Aug 2009

Liu Peng-Yuan, Vikis Haris, James Michael, Lu Yan, Wang Dao-Long, Liu Hong-Bo, Wen Wei-Dong, Wang Yian, You Ming

Abstract excerpt

Lung cancer is the leading cause of cancer death worldwide. Here, we describe a genome-wide association study of chemically induced lung tumorigenesis on 593 mice from 21 inbred strains using 115,904 genotyped and 1,952,918 imputed single nucleotide polymorphisms (SNPs). Using a genetic backgroun...

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PMID: 19622765
DOI: 10.1158/0008-5472.CAN-09-0782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19622765-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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