Article
Genome-wide analysis of the mouse lung transcriptome reveals novel molecular gene interaction networks and cell-specific expression signatures.
Respiratory research - 2 May 2011
Alberts Rudi, Lu Lu, Williams Robert W, Schughart Klaus
Abstract excerpt
BACKGROUND: The lung is critical in surveillance and initial defense against pathogens. In humans, as in mice, individual genetic differences strongly modulate pulmonary responses to infectious agents, severity of lung disease, and potential allergic reactions. In a first step towards understanding genetic predisposition and pulmonary molecular networks that underlie individual differences in disease...
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