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Article

Gene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer.

Cell reports - 26 Jul 2016

Quigley David A, Kandyba Eve, Huang Phillips, Halliwill Kyle D, Sjölund Jonas, Pelorosso Facundo, Wong Christine E, Hirst Gillian L, Wu Di, Delrosario Reyno, Kumar Atul, Balmain Allan

Abstract excerpt

Inherited germline polymorphisms can cause gene expression levels in normal tissues to differ substantially between individuals. We present an analysis of the genetic architecture of normal adult skin from 470 genetically unique mice, demonstrating the effect of germline variants, skin tissue location, and perturbation by exogenous inflammation or tumorigenesis on gene signaling pathways. Gene networks related to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27425619
DOI: 10.1016/j.celrep.2016.06.061
PMCID: PMC5087975

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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