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Article

Insight into determinants of substrate binding and transport in a multidrug efflux protein.

Scientific reports - 10 Mar 2016

Alegre Kamela O, Paul Stephanie, Labarbuta Paola, Law Christopher J

Abstract excerpt

Multidrug resistance arising from the activity of integral membrane transporter proteins presents a global public health threat. In bacteria such as Escherichia coli, transporter proteins belonging to the major facilitator superfamily make a considerable contribution to multidrug resistance by catalysing efflux of myriad structurally and chemically different antimicrobial compounds. Despite their clinical...

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Identifiers

PMID: 26961153
DOI: 10.1038/srep22833
PMCID: PMC4785361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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