Article
Characterization of the multidrug efflux transporter styMdtM from Salmonella enterica serovar Typhi.
Proteins - 1 Sept 2021
Shaheen Aqsa, Ismat Fouzia, Iqbal Mazhar, Haque Abdul, Ul-Haq Zaheer, Mirza Osman, De Zorzi Rita, Walz Thomas, Rahman Moazur
Abstract excerpt
Salmonellae are foodborne pathogens and the major cause of gastroenteritis in humans. Salmonellae express multidrug efflux transporters that play a key role in their drug resistance, which is becoming an increasing problem for therapeutic intervention. Despite their biomedical importance, the mechanisms underlying substrate transport by multidrug efflux transporters remain poorly understood. Here, we describe the...
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