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Article

Major facilitator superfamily efflux pumps in human pathogens: Role in multidrug resistance and beyond

1 Jan 2024

Abstract excerpt

The major facilitator superfamily (MFS) of proteins constitutes a large group of related solute transporters found across all known living taxa of organisms. The transporters of the MFS contain an extremely diverse array of substrates, including ions, molecules of intermediary metabolism, and structurally different antimicrobial agents. First discovered over 30 years ago, the MFS represents an important...

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PMID: 38974671
DOI: 10.1016/j.crmicr.2024.100248

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