Article
Mechanistic insights into genetic susceptibility to prostate cancer.
Cancer letters - 1 Dec 2021
Tian Pan, Zhong Mengjie, Wei Gong-Hong
Abstract excerpt
Prostate cancer (PCa) is the second most common cancer in men and is a highly heritable disease that affects millions of individuals worldwide. Genome-wide association studies have to date discovered nearly 270 genetic loci harboring hundreds of single nucleotide polymorphisms (SNPs) that are associated with PCa susceptibility. In contrast, the functional characterization of the mechanisms underlying PCa risk...
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