Article
Apolipoprotein(a) Kringle-IV Type 2 Copy Number Variation Is Associated with Venous Thromboembolism.
PloS one - 1 Jan 2016
Sticchi Elena, Magi Alberto, Kamstrup Pia R, Marcucci Rossella, Prisco Domenico, Martinelli Ida, Mannucci Pier Mannuccio, Abbate Rosanna, Giusti Betti
Abstract excerpt
In addition to the established association between high lipoprotein(a) [Lp(a)] concentrations and coronary artery disease, an association between Lp(a) and venous thromboembolism (VTE) has also been described. Lp(a) is controlled by genetic variants in LPA gene, coding for apolipoprotein(a), including the kringle-IV type 2 (KIV-2) size polymorphism. Aim of the study was to investigate the role of LPA gene KIV-2...
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