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Article

The apolipoprotein (a) gene: a transcribed hypervariable locus controlling plasma lipoprotein (a) concentration.

Human genetics - 1 Nov 1992

Kraft H G, Köchl S, Menzel H J, Sandholzer C, Utermann G

Abstract excerpt

Lipoprotein(a) [Lp(a)] is a quantitative trait in human plasma. Lp(a) consists of a low-density lipoprotein and the plasminogen-related apolipoprotein(a) [apo(a)]. The apo(a) gene determines a size polymorphism of the protein, which is related to Lp(a) levels in plasma. In an attempt to gain a deeper insight into the genetic architecture of this risk factor for coronary heart disease, we have investigated the...

Topics

Alleles
Apolipoproteins A
Base Sequence
Chromosome Mapping
DNA
Deoxyribonucleases, Type II Site-Specific
Electrophoresis, Gel, Pulsed-Field
Exons
Gene Frequency
Humans
Introns

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipoprotein(a)

Molecular Sequence Data

Peptide Fragments

Polymerase Chain Reaction

Polymorphism, Genetic

Source

Identifiers

PMID: 1336760
DOI: 10.1007/BF00220066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1336760-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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