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Article

Lipoprotein (a) as a cause of cardiovascular disease: insights from epidemiology, genetics, and biology.

Journal of lipid research - 1 Nov 2016

Nordestgaard Børge G, Langsted Anne

Abstract excerpt

Human epidemiologic and genetic evidence using the Mendelian randomization approach in large-scale studies now strongly supports that elevated lipoprotein (a) [Lp(a)] is a causal risk factor for cardiovascular disease, that is, for myocardial infarction, atherosclerotic stenosis, and aortic valve stenosis. The Mendelian randomization approach used to infer causality is generally not affected by confounding and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27677946
DOI: 10.1194/jlr.R071233
PMCID: PMC5087876

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