Article
Lipoprotein(a): resurrected by genetics.
Journal of internal medicine - 1 Jan 2013
Kronenberg F, Utermann G
Abstract excerpt
Plasma lipoprotein(a) [Lp(a)] is a quantitative genetic trait with a very broad and skewed distribution, which is largely controlled by genetic variants at the LPA locus on chromosome 6q27. Based on genetic evidence provided by studies conducted over the last two decades, Lp(a) is currently considered to be the strongest genetic risk factor for coronary heart disease (CHD). The copy number variation of kringle IV...
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