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Article

Genetic basis and pathophysiological implications of high plasma Lp(a) levels.

Journal of internal medicine - 1 Jun 1992

Scanu A M

Abstract excerpt

Lipoprotein(a) or Lp(a) is a genetic variant of plasma low density lipoproteins (LDL) containing apoB100 covalently linked to apolipoprotein(a) or apo(a), the specific marker of Lp(a). Lp(a) is heterogeneous in size and density, accounting in part for the marked size polymorphism of apo(a), 300 to 800 kDa. The apo(a) size polymorphism is related to the different number of kringle repeats which are structurally...

Topics

Alleles
Arteriosclerosis
Genetic Variation
Humans
Lipoprotein(a)
Lipoproteins
Lipoproteins, LDL
Plasminogen
Polymorphism, Genetic
Risk Factors
Thrombosis

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Identifiers

PMID: 1535652
DOI: 10.1111/j.1365-2796.1992.tb01257.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1535652-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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