Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Genetics and the Causal Role of Lipoprotein(a) for Various Diseases.

Cardiovascular drugs and therapy - 1 Feb 2016

Kronenberg Florian

Abstract excerpt

Lipoprotein(a) [Lp(a)] is a highly atherogenic lipoprotein that is under strong genetic control by the LPA gene locus. Genetic variants including a highly polymorphic copy number variation of the so called kringle IV repeats at this locus have a pronounced influence on Lp(a) concentrations. High concentrations of Lp(a) as well as genetic variants which are associated with high Lp(a) concentrations are both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Diseases
Share to DNA Copy Number Variations
Share to LPA gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Genetic Predisposition to Disease

Share to Genetics, Medical

Share to Lipoprotein(a)

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 26896185
DOI: 10.1007/s10557-016-6648-3
PMCID: PMC4789197

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Genetics and the Causal Role of Lipoprotein(a) for Various Diseases.PMID 26896185Read ↗

Lipoprotein (a) as a cause of cardiovascular disease: insights from epidemiology, genetics, and biology.Semantic proximity Read ↗

Lipoprotein(a): resurrected by genetics.Semantic proximity Read ↗

Lipoprotein(a): from Causality to Treatment.Semantic proximity Read ↗

Mendelian Randomization: Principles and its usage in Lp(a) research.Semantic proximity Read ↗

Evaluating genetically-predicted causal effects of lipoprotein(a) in human diseases: a phenome-wide Mendelian randomization studySemantic proximity Read ↗

Genetics and Pathophysiological Mechanisms of Lipoprotein(a)-Associated Cardiovascular Risk.Semantic proximity Read ↗

Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis.Semantic proximity Read ↗

Lipoprotein(a): the revenantSemantic proximity Read ↗

Prediction of cardiovascular risk by Lp(a) concentrations or genetic variants within the LPA gene regionSemantic proximity Read ↗

[Lipoprotein(a) - the hereditary risk factor for cardiovascular disease].Semantic proximity Read ↗

Proteomic Insights into Lp(a) Cardiovascular Mechanisms: A Mendelian Randomization StudySemantic proximity Read ↗

Lipoprotein(a): more interesting than ever after 50 years.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.