Article
DNA methylation contributes to natural human variation.
Genome research - 1 Sept 2013
Heyn Holger, Moran Sebastian, Hernando-Herraez Irene, Sayols Sergi, Gomez Antonio, Sandoval Juan, Monk Dave, Hata Kenichiro, Marques-Bonet Tomas, Wang Liewei, Esteller Manel
Abstract excerpt
DNA methylation patterns are important for establishing cell, tissue, and organism phenotypes, but little is known about their contribution to natural human variation. To determine their contribution to variability, we have generated genome-scale DNA methylation profiles of three human populations (Caucasian-American, African-American, and Han Chinese-American) and examined the differentially methylated CpG...
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