Article

Graph-based data integration predicts long-range regulatory interactions across the human genome

2014-04-29

Abstract excerpt

Transcriptional regulation of gene expression is one of the main processes that affect cell diversification from a single set of genes. Regulatory proteins often interact with DNA regions located distally from the transcription start sites (TSS) of the genes. We developed a computational method that combines open chromatin and gene expression information for a large number of cell types to identify these distal re...

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Literature Corpus work: bbc5216a-4c6f-5154-990e-2300240f510b
DOI: 10.1101/004622

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