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Article

Acquired TERT promoter mutations stimulate TERT transcription in mantle cell lymphoma.

American journal of hematology - 1 May 2016

Panero Julieta, Alves-Paiva Raquel M, Roisman Alejandro, Santana-Lemos Barbara A, Falcão Roberto P, Oliveira Gustavo, Martins Diego, Stanganelli Carmen, Slavutsky Irma, Calado Rodrigo T

Abstract excerpt

Mantle cell lymphoma (MCL) is an aggressive lymphoid neoplasm with poor prognosis. Acquired telomerase reverse transcriptase gene promoter (TERTp) mutations are among the most frequent somatic non-coding mutations in cancers. In this study, the prevalence of TERTp mutations in 24 MCL and 21 other lymphoid neoplasias (oLN) was investigated. Eight MCL samples (33%) carried TERTp mutations, two homozygous and six...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26852175
DOI: 10.1002/ajh.24324

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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