Telomerase reverse transcriptase promoter mutations in cancers derived from multiple organ sites among middle eastern population.

doi:10.1016/j.ygeno.2019.09.017

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Telomerase reverse transcriptase promoter mutations in cancers derived from multiple organ sites among middle eastern population.

Genomics - 1 Mar 2020

Siraj Abdul K, Bu Rong, Iqbal Kaleem, Parvathareddy Sandeep Kumar, Siraj Nabil, Siraj Sarah, Diaz Mark Ranier F, Rala Dionne Rae, Benito Allianah D, Sabido Maria Angelita, Al-Rasheed Maha, Al-Obaisi Khadija A S, Al-Haqawi Wael, Victoria Ingrid G, Al Balawy Wafaa, Abedalthagafi Malak, Wakil Salma Majid, Ajarim Dahish, Mohammed Shamayel, Alhussain Turki, Tulbah Asma, Al-Badawi Ismail A, Al-Dayel Fouad, Al-Kuraya Khawla S

Abstract excerpt

Sanger Sequencing and immunohistochemistry was employed to investigate the TERT promoter mutations and TERT protein expression with their association to clinicopathological characteristics in over 2200 samples of Middle Eastern origin from 13 different types of cancers. The TERT promoter mutations were most frequently present in bladder cancer (68.6%), followed by central nervous system tumors (28.7%), thyroid...

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Identifiers

PMID: 31669704
DOI: 10.1016/j.ygeno.2019.09.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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