Immortalization by truncated myc or ras genes and synergism between myc and ras genes in cell transformation.

Article

Immortalization by truncated myc or ras genes and synergism between myc and ras genes in cell transformation.

Anticancer research - 1 Jan 2000

Spandidos D A, Lang J C

Abstract excerpt

Human c-myc and normal or mutant T24 H-ras1 genes either linked to the regulatory sequences of the human metallothionein IIa gene or unlinked have been employed individually or in combination to transfect early passage Chinese hamster lung cells. Since the c-myc and H-ras1 genes are present in re...

Topics

Animals
Cell Line
Cell Transformation, Neoplastic
Cricetinae
Genes
Genes, ras
Humans
Metallothionein
Mutation
Plasmids
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-myc
Proto-Oncogenes
Regulatory Sequences, Nucleic Acid
Transfection

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