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Article

Synergism between pairs of immortalizing genes in transformation assays of rat embryo fibroblasts.

Oncogene - 1 Dec 1990

Peacock J W, Matlashewski G J, Benchimol S

Abstract excerpt

A number of cellular and viral genes encode proteins that play a role in the establishment of normal cells in culture. In addition, these genes cooperate with activated ras genes to induce cellular transformation. We show that ras-dependent transformation of rat embryo fibroblasts is more efficient when two establishment genes are used together compared with one alone. Both quantitative and qualitative...

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PMID: 2178238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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