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Article

Expression of Rap 1 suppresses genomic instability of H-ras transformed mouse fibroblasts.

Somatic cell and molecular genetics - 1 Mar 1997

Wani M A, Denko N C, Stambrook P J

Abstract excerpt

Among the multiple genetic changes that occur during cancer progression are the activation of proto-oncogenes and the inactivation or loss of genes encoding tumor suppressors. The potential roles for these genes in the perturbation of genome stability continues to be of major interest. We have previously shown that conditional expression of H-ras in NIH3T3 cells increases genetic instability in these cells,...

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Identifiers

PMID: 9330640
DOI: 10.1007/BF02679971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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