Inactivation of a tumor suppressor function in immortal Syrian hamster cells by N-methyl-N'-nitro-N-nitrosoguanidine and by 5-aza-2'-deoxycytidine.

doi:10.1093/carcin/14.2.285

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Article

Inactivation of a tumor suppressor function in immortal Syrian hamster cells by N-methyl-N'-nitro-N-nitrosoguanidine and by 5-aza-2'-deoxycytidine.

Carcinogenesis - 1 Feb 1993

West R W, Barrett J C

Abstract excerpt

Clonal lines of immortal Syrian hamster cells were previously isolated that either suppressed (supB+) tumorigenicity in hybrids with a malignant hamster cell line (BP6T) or had lost this suppression ability (supB-). Neither line was tumorigenic or showed anchorage-independent growth in normal gro...

Topics

Animals
Antineoplastic Agents
Azacitidine
Cell Adhesion
Cell Division
Cell Line
Cell Transformation, Neoplastic
Cells, Cultured
Cricetinae
Decitabine
Embryo, Mammalian
Epidermal Growth Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression Regulation, Neoplastic

Genes, Tumor Suppressor

Insulin

Mesocricetus

Methylnitronitrosoguanidine

Mice

Source

Open in PubMed

Identifiers

PMID: 7679613
DOI: 10.1093/carcin/14.2.285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7679613-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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