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Article

Myeloid interferon-γ receptor deficiency does not affect atherosclerosis in LDLR(-/-) mice.

Atherosclerosis - 1 Mar 2016

Boshuizen Marieke C S, Neele Annette E, Gijbels Marion J J, van der Velden Saskia, Hoeksema Marten A, Forman Ruth A, Muller Werner, Van den Bossche Jan, de Winther Menno P J

Abstract excerpt

BACKGROUND AND AIMS: Atherosclerosis is a chronic lipid-driven inflammatory disease of the arterial wall. Interferon gamma (IFNγ) is an important immunomodulatory cytokine and a known pro-atherosclerotic mediator. However, cell-specific targeting of IFNγ or its signaling in atherosclerosis development has not been studied yet. As macrophages are important IFNγ targets, we here addressed the involvement of myeloid...

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Source

Identifiers

PMID: 26828750
DOI: 10.1016/j.atherosclerosis.2016.01.026

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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